EXTRACTA PARTNERING POLICY

EXTRACTA seeks dynamic partnerships in accordance with Client interest and the needs of
Company projects. Partnerships with INDUSTRY, with ACADEMIC INSTITUTIONS and
GOVERNMENT in specifically funded projects are the main types of effort developed in the
Company.

PARTNERING WITH INDUSTRY

Research Collaboration Contracts relate to bioprospection performed on the EXTRACTA
Bank of Chemical Biodiversity. Such contracts may entail R&D activities fully carried out by
EXTRACTA (as was the case of the recently completed 1999 contract with GlaxoSmithKline,
see News & Landmarks) or carried out in part by the Client at its home labs.

Other partnerships with Industry relate to the characterization of plant drugs and essences 
as a basis for development of Phytotherapics and Cosmetics. Such collaboration may encompass
the assembly of specific supply chains and fostering of productive activity in local communities.

PARTNERING WITH ACADEMIA

EXTRACTA network of Academic Partners is strongly based within Rio de Janeiro and specially
involves UFRJ, although it extends to other States and to other countries. This varied assembly
of internationally recognized laboratories open for EXTRACTA R&D interactions in several fields
of its endeavor, such as:

 Structural Characterization and Medicinal Chemistry of Bioactive Compounds

 Study and Validation of New Targets in Cardiovascular, CNS, Degenerative and Immunological Disease

 Innovative Bioassays for HTS and novel technology for Pre-clinical “in vitro” ADMeTox.

 Botanical Certification, Natural Compound Profiling and technology development for quality control and
commercial production: Phytotherapics and Cosmeceuticals.
           
 New Materials of interest different segments of Industry

 Nanotechnology Applications for the enhancement of Bioactivity of Natural Products

 Novel Applications of bioactive plant Small Molecules as markers, inhibitors and modulators in Genomics,
Proteomics, Metabolomics, Tissue Engineering and Stem Cell Research

BOARD OF SCIENTIFIC ADVISORS

 PHYTOCHEMISTRY
Prof. Angelo da Cunha Pinto
Full Professor at the UFRJ Institute of Chemistry

 CELL BIOLOGY
Radovan Borojevic
Full Professor at the UFRJ Institute for Biomedical Sciences

 BIODIVERSITY ACCESS
Benjamin Gilbert
Head, Natural Products Chemistry Laboratory, at FIOCRUZ-FARMANGUINHOS

 PHYSIOLOGY AND PHARMACOLOGY
Eliete Bouskela
Professor of Physiology and Head, Microcirculation Laboratory
State University of Rio de Janeiro

ACADEMIC INSTITUTIONS COLLABORATIVE NETWORK

 Universidade Federal do Rio de Janeiro
Instituto de Biofísica Carlos Chagas Filho
Instituto de Microbiologia Paulo de Góes
Instituto de Biologia (Herbário RFA, Credenciado pelo CGEN/MMA)
Instituto de Ciências Biomédicas
Instituto de Química

 Universidade Federal do Pará
Departamento de Química e Central de Extração

 Museu Paraense Emilio Goeldi
Herbário Credenciado pelo CGEN/MMA

GOVERNMENTAL R&D PROMOTION AGENCIES

 FAPERJ - Fundação Carlos Chagas Filho de Amparo à Pesquisa
do Estado do Rio de Janeiro

 Fundação Bio-Rio

 FADESP - Fundação de Amparo ao Desenvolvimento de Pesquisa
                (Universidade Federal do Pará)

 FINEP - Financiadora do Estudo e Projetos

GOVERNAMENTAL REGULATORY AGENCY

 CGEN - Conselho de Gestão do Patrimônio Genético / Ministério do Meio Ambiente

INDUSTRY REPRESENTATION ENTITY

 ABRABI - Associação Brasileira das Empresas de Biotecnologia.

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